Christian Blouin's lab, Dalhousie University

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BIOC 4700/5700 - Proteins

Learning Sessions

Session 1 - Thermodynamic Equlibria and protein dynamics

Learning Outcome

Session 2 - Intrinsic disorder and protein binding

Please read the following paper:
When the Scaffold Cannot Be Ignored: The Role of the Hydrophobic Core in Ligand Binding and Specificity.

Session 3 - Simulating proteins

Learning Outcome

Session 4 - Protein design

Please read the following paper:
Protein folding and de novo protein design for biotechnological applications

Session 5 - Modularity and rational design

Learning Outcomes

Session 6 - Directed evolution and design

Please read the following paper:
Negative selection and stringency modulation in phage-assisted continuous evolution.